Rapid decline in episodic memory in healthy older adults with high amyloid-β.
نویسندگان
چکیده
High levels of amyloid-β (Aβ) have been associated with greater rates of decline in episodic memory over 18 months in healthy older adults. Serial assessments over shorter time intervals may facilitate earlier detection of Aβ-related memory decline in healthy older adults. In forty-four healthy older adults enrolled in the Australian Imaging, Biomarkers and Lifestyle Rate of Change Sub-Study, we compared rates of change in cognition over six months in healthy older adults with high and low levels of Aβ. High Aβ was associated with greater decline in episodic memory measures over 6 months in healthy older adults.
منابع مشابه
Stronger effect of amyloid load than APOE genotype on cognitive decline in healthy older adults.
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عنوان ژورنال:
- Journal of Alzheimer's disease : JAD
دوره 33 3 شماره
صفحات -
تاریخ انتشار 2013